期刊
JOURNAL OF MAGNETIC RESONANCE IMAGING
卷 18, 期 2, 页码 175-180出版社
WILEY
DOI: 10.1002/jmri.10346
关键词
magnetic resonance imaging; susceptibility; MR-venography; BOLD; phase-unwrapping; 3 Tesla
Purpose: To improve the diagnostic value of BOLD MR-Venography by removing artifacts related to phase wrapping. particularly in regions of large background susceptibilities at high magnetic field strengths. Materials and Methods: High resolution, T-2*-weighted, single echo images were acquired on a 3 T system (Medspec 30/80 Avance. Bruker Medical. Ettlingen, Germany) with a three-dimensional. first order velocity compensated gradient echo sequence using a quadrature transmit/receive birdcage head coil. Data of nine healthy subjects and 19 patients were evaluated (age range: 27 to 76 years). To achieve improved MR-venograms, a fully automated region-growing phase unwrapping algorithm and subsequent high pass filtering were applied to phase images prior to the computation of minimum intensity projections. Results: Considerably improved visualization of venous structures in regions of large background susceptibility-induced field inhomogeneities is demonstrated in healthy subjects and patients with brain tumors. Conclusion: BOLD MR venograms are improved compared to previous post-processing algorithms. It is now feasible to obtain high-resolution images also in inhomogeneous regions, which increases the clinical potential of BOLD MR-Venography.
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