Toxoplamosis transmitted to a newborn from the mother infected 20 years earlier

PURPOSE: To present a case of congenital toxoplasmosis in a newborn whose mother had a 20,year history of a chorioretinal macular scar and positive serology for toxoplasmosis. DESIGN/METHODS: Case report. SETTING/RESULTS: A 38-year-old woman who had been treated for ocular toxoplasmosis 20 years earlier delivered a newborn who presented with a focal necrotizing retinochoroiditis characteristic of toxoplasmosis, as well as positive immunoglobulin (Ig) G and M serology for toxoplasmosis. The workup was negative for other entities. CONCLUSION: This case suggests that women with old retinal scars due to toxoplasmosis and long,standing IgG antibodies to toxoplasmosis are also at risk of transmitting this disease to the fetus.