期刊
CURRENT OPINION IN STRUCTURAL BIOLOGY
卷 13, 期 4, 页码 453-466出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-440X(03)00107-6
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资金
- NIAID NIH HHS [AI30557, R37 AI030557] Funding Source: Medline
The fusion of biological membranes is governed by the carefully orchestrated interplay of membrane proteins and lipids. Recently determined structures of fusion proteins, individual domains of fusion proteins and their complexes with regulatory proteins and membrane lipids have yielded much suggestive insight into how viral and intracellular membrane fusion might proceed. These structures may be combined with new knowledge on the fusion of pure lipid bilayer membranes in an attempt to begin to piece together the complex puzzle of how biological membrane fusion machines operate on membranes.
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