The dynamical response of an atomic Bose-Einstein condensate manipulated by an integrated atom-optics device, such as a microtrap or a microfabricated waveguide, is studied. We show that when the miniaturization of the device enforces a sufficiently high condensate density, three-body interactions lead to a spatial modulational instability that results in a fundamental limit on the coherent manipulation of Bose-Einstein condensates.
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