Discovery of the first series of inhibitors of human papillomavirus type 11:: Inhibition of the assembly of the E1-E2-origin DNA complex

We have discovered a series of inhibitors of the assembly of the HPV11 E1-E2-origin DNA complex, which incorporate an indandione fused to a substituted tetrahydrofuran. (C) 2003 Elsevier Ltd. All rights reserved.