期刊
ORGANIC LETTERS
卷 5, 期 16, 页码 2849-2852出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol034894e
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资金
- NCI NIH HHS [CA 60548] Funding Source: Medline
Graphics Methods for functionalization of the D ring of diene 1 were investigated. This study led to efficient syntheses of 3 and the subsequent 23'-deoxy,17'alpha-hydroxy cephalostatin 1 analog (4). The bioactivity data of 2 and 4 are in the low nanomolar range for a 10-cell-line minipanel.
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