期刊
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
卷 89, 期 10, 页码 1907-1912出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.apmr.2008.05.010
关键词
Arm; Prosthesis implantation; Radial nerve; Rehabilitation; Stroke
资金
- Alfred Mann Foundation
Objective: To investigate the feasibility of implanting microstimulators to deliver programmed nerve stimulation for sequenced muscle activation to recover arm-hand functions. Design: By using a minimally invasive procedure and local anesthesia, 5 to 7 microstimulators can be safely and comfortably implanted adjacent to targeted radial nerve branches in the arm and forearm of 7 subjects with poststroke paresis. The microstimulators' position should remain stable with no tissue infection and can be programmed to produce effective personalized functional muscle activity with no discomfort for a preliminary 12-week study. Clinical testing, before and after the study, is reported in the accompanying study. Setting: Microstimulator implantations in a sterile operating room. Participants: Seven adults, with poststroke hemiparesis of 12 months or more. Intervention: Under local anesthesia, a stimulating probe was inserted to identify radial nerve branches. Microstimulators were inserted by using an introducer and were retrievable for 6 days by attached suture. Each device was powered via a radiofrequency link from 2 external cuff coils connected to a control unit. Main Outcome Measures: To achieve low threshold values at the target sites with minimal implant discomfort. Microstimulators and external equipment were monitored over 12 weeks of exercise. Results: Seven subjects were implanted with 41 microstimulators, 5 to 7 per subject, taking 3.5 to 6 hours. Implantation pain levels were 20% more than anticipated. No infections or microstimulator failures occurred. Mean nerve thresholds ranged between 4.0 to 7.7 mu coulomb/cm(2)/phase over 90 days, indicating that cathodes were within 2 to 4mm of target sites. In I subject, 2 additional microstimulators were inserted. Conclusions: Microstimulators were safely implanted with no infection or failure. The system was reliable and programmed effectively to perform exercises at home for functional restoration.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据