4.7 Article

Facile synthesis of flavonoid 7-O-glycosides

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JOURNAL OF ORGANIC CHEMISTRY
卷 68, 期 17, 页码 6842-6845

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AMER CHEMICAL SOC
DOI: 10.1021/jo034553e

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Highly regioselective removal of the 7-O-acylgroups of the peracyated flavones, isoflavones, and flavonolsyl(PhSH, imidazole, NMP) followed by effective glycosylation with glycosyl trifluoroacetimidates (BF3.Et2O) and cautious deprotection of the acyl groups under basic conditions afforded the desired 7-O-flavonoid glycosides in satisfactory yields.

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