Two New Acorane Sesquiterpenes from Illicium henryi

Two new acorane sesquiterpenes, 10-hydroxyacoronene (1) and 1 beta-isopropyl-4 beta-methyl-9 beta-hydroxy spiro[4.5]dec-6-en-8-one (2), one new natural product, 4-hydroxy-4, 6-dimethyl-1-tetralone (3), and one known acorane sesquiterpene, acoradiepoxide (4) were isolated from the twigs and leaves of Illicium henryi. The structures of the new compounds were elucidated primarily on the basis of analysis of spectroscopic data. In addition, the inhibitory effect on NO production of these compounds were tested. Compounds 1 and 4 exhibited slight inhibitory effects on NO production with IC50 values of 82.4 mu g/ml, and 76.5 mu g/ml, respectively.