期刊
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
卷 47, 期 9, 页码 2984-2986出版社
AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.47.9.2984-2986.2003
关键词
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The triple-base-pair 16S rDNA mutation AGA(926-928)-->TTC mediates high-level tetracycline resistance in Helicobacter pylori. In contrast, single- and double-base-pair mutations mediated only low-level tetracycline resistance and decreased growth rates in the presence of tetracycline, explaining the preference for the TTC mutation in tetracycline-resistant H. pylori isolates.
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