期刊
CANADIAN JOURNAL OF ANIMAL SCIENCE
卷 83, 期 3, 页码 493-500出版社
AGRICULTURAL INST CANADA
DOI: 10.4141/A03-008
关键词
pig; ergot; alkaloid; toxicity; performance; prolactin
The present study investigated the effect of ergot alkaloids on performance and clinical symptoms in weaned pigs. Wheat ergot sclerotia (1880 mg alkaloid kg(-1); ergocristine, ergotamine, ergosine, ergocryptine, and ergocornine constituting 40, 36, 11, 7, and 6% of the total, respectively) were added on a weight basis to a basal diet at 0.00 (control), 0.05, 0.10, 0.25, 0.50, and 1.00% and fed to 192 weaned pigs (20.4 +/- 3.4 d; 6.9 +/- 1.3 kg; mean +/- SD) for 28 d, beginning 7 d post-weaning. Pigs fed the 1.00% diet gained 82 and 38% less than the control (P < 0.001, 211 vs. 39 g d(-1), wk 1 and 432 vs. 269 9 d(-1), wk 2) and body weight on day 28 was reduced quadratically by alkaloids (P < 0.005). Ergot alkaloids decreased average daily feed intake (ADFI) quadratically (P < 0.04) and feed efficiency linearly (P < 0.03) (0.62 vs. 0.44; control vs. 1.00%) over the entire period, but ADFI was not affected during the initial 14 d (P > 0.20). Ergot alkaloids decreased serum prolactin quadratically (P < 0.002) and urea nitrogen concentrations (P < 0.05). The maximum tolerable ergot level in the diet was 0.10 and 0.05% based on average daily gain (ADG) and ADFI, respectively, corresponding to 2.07 mg and 1.04 mg alkaloid kg(-1) diet.
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