The adsorption of drugs on silica aerogels has been investigated. Adsorption takes place from the solution of a corresponding drug in supercritical CO2. Adsorption isotherms were measured for one model substance, naphthalene, and two drugs, ketoprofen and miconazole, at 40 C. It has been shown that both drugs exhibit a high affinity to silica aerogel what gives a possibility to use aerogels as a drug carrier in aerogel-drug formulations. The knowledge of the adsorption isotherm allows to control the loading of aerogels with drugs in such formulations. Both hydrophilic and hydrophobic aerogels can be used as a carrier. The influence of the hydrophobicity of the carrier material on the adsorption process is discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据