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The evolution of a resistant pathogen - the case of MRSA

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CURRENT OPINION IN PHARMACOLOGY
卷 3, 期 5, 页码 474-479

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ELSEVIER SCI LTD
DOI: 10.1016/S1471-4892(03)00109-7

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Recent advances in molecular epidemiological methods have elucidated the evolutionary pathways by which modern methicillin-resistant Staphylococcus aureus have evolved. Only five major lineages of hospital methicillin-resistant Staphylococcus aureus exist, but these are globally distributed and evolving resistance to even the newest antibiotics.

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