期刊
LEUKEMIA RESEARCH
卷 27, 期 10, 页码 871-876出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0145-2126(03)00023-7
关键词
inherited susceptibility; chronic lymphocytic leukemia
In Western countries B-cell chronic lymphocytic leukemia (CLL) is the most common form of leukemia. Evidence from epidemiological studies and family studies strongly supports the notion that a subset of CLL involves inherited susceptibility. Identification of genes predisposing to CLL should be useful for diagnosis and treatment, as well as serving as a model for B-cell tumorigenesis in general. Here, we review the current status of knowledge about inherited susceptibility to CLL. (C) 2003 Elsevier Science Ltd. All rights reserved.
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