期刊
NEWS IN PHYSIOLOGICAL SCIENCES
卷 18, 期 -, 页码 201-204出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/nips.01448.2003
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- NIDDK NIH HHS [DK 43785, DK 44510, R01 DK044510, R01 DK044510-10] Funding Source: Medline
Mucosal proliferation, together with differentiation and apoptosis, are a continuous homeostatic process in the intestinal epithelium. The glutathione/glutathione disulfide redox status plays a key role in intestinal growth control wherein a reduced redox potential maintains a proliferative state. An oxidative shift in this potential elicits growth arrest and cell transition to a differentiated or apoptotic phenotype.
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