期刊
JOURNAL OF MAGNETIC RESONANCE
卷 164, 期 2, 页码 321-328出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/S1090-7807(03)00186-1
关键词
longitudinal relaxation; T-1; single-scan; one-shot
资金
- NCRR NIH HHS [RR-00995] Funding Source: Medline
- NIGMS NIH HHS [GM-38352] Funding Source: Medline
- NINDS NIH HHS [F32 NS42425-01] Funding Source: Medline
Several single-scan experiments for the measurement of the longitudinal relaxation time (T-1) are proposed. These experiments result in fast and accurate determinations of the relaxation rate, are relatively robust to pulse imperfections, and preserve information about the chemical shift. The method used in these experiments is to first encode the T-1 values as a spatial variation of the magnetization and then to read out this variation either by applying a weak gradient during acquisition or by sequentially observing different slices of the sample. As a result, it is possible to reduce the time necessary to determine the T-1 values by one or two orders of magnitude. This time saving comes at the expense of the signal-to-noise level of the resulting spectrum and some chemical shift resolution. (C) 2003 Elsevier Science (USA). All rights reserved.
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