期刊
BIOORGANIC & MEDICINAL CHEMISTRY
卷 11, 期 20, 页码 4487-4501出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0968-0896(03)00456-5
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资金
- NCI NIH HHS [CA 63536] Funding Source: Medline
A series of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues lacking the benzoylglutamate subunit were prepared and examined as potential inhibitors of glycinamide ribonucleotide transformylase (GAR Tfase) and aminoimidazole carboxamide transformylase (AICAR Tfase). (C) 2003 Elsevier Ltd. All rights reserved.
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