期刊
COMPTES RENDUS BIOLOGIES
卷 326, 期 10-11, 页码 993-1001出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.crvi.2003.09.014
关键词
functional genomics; fluorescence protein; human full length cDNA; image processing; protein localization; pattern classification; subspace method
类别
The sequence of the human genome has been determined. The next task is to determine the function of the genes. Classifying cellular forms of proteins encoded by human cDNA clones is a primary step toward understanding the biological role of proteins and their coding genes. We report here our ongoing work on an automatic system to facilitate this classification. Our system handles the transfection, incubation, acquisition of microscopic images of the cells, and the classification of forms there appearing in the images. Our system correctly classified proteins by their forms at a rate of 90% in feasibility studies. (C) 2003 Academie des sciences. Published by Elsevier SAS. All rights reserved.
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