期刊
JOURNAL OF INFECTIOUS DISEASES
卷 188, 期 7, 页码 1054-1058出版社
UNIV CHICAGO PRESS
DOI: 10.1086/378203
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资金
- NIDDK NIH HHS [K23-DK-02660, R01-DK-43134, P01-DK-53369] Funding Source: Medline
The vaginal ecology of 463 community-dwelling postmenopausal women was characterized. Vaginal lactobacilli were present in 62% of the women and were significantly more prevalent among women receiving hormone replacement therapy during the previous year. Vaginal Escherichia coli and enterococci were each present in 39% of women and were significantly more frequent in women with a history of urinary tract infection. Heavy growth of lactobacilli was associated with a lower frequency of vaginal colonization with E. coli. Thus, postmenopausal women have a relative depletion of vaginal lactobacilli and an increase in vaginal E. coli compared with premenopausal women.
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