期刊
NEUROIMAGE
卷 20, 期 2, 页码 1020-1025出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/S1053-8119(03)00356-2
关键词
acoustics; cognition; L1 Minimum-Norm Current Estimate (MNCE); Magnetic Mismatch Negativity (MMN); language; lexical processing; spoken word
The inferior frontal and superior temporal areas in the left hemisphere are well-known to be crucial for language processing in most right-handed individuals. This has been established by classical neurological investigations and neuropsychological studies along with metabolic brain imaging have recently revealed converging evidence. Here, we use fast neurophysiological brain imaging, magnetoen-cephalography (MEG), and L1 Minimum-Norm Current Estimates to investigate the time course of cortical activation underlying the magnetic Mismatch Negativity elicited by a spoken word. Left superior-temporal areas became active 136 ms after the information in the acoustic input was sufficient for identifying the word, and activation of the left inferior-frontal cortex followed after an additional delay of 22 ms. By providing answers to the where- and when-questions of cortical activation, MEG recordings paired with current estimates of the underlying cortical sources may advance our understanding of the spatiotemporal dynamics of distributed neuronal networks involved in cognitive processing in the human brain. (C) 2003 Elsevier Inc. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据