Simple evaluation of the wound healing activity of a crude extract of Portulaca oleracea L. (growing in Jordan) in Mus musculus JVI-1

The preliminary wound healing activity of Portulaca oleracea was studied using Mus musculus JVI-1. For this purpose fresh homogenized crude aerial parts of Portulaca oleracea were applied topically on the excision wound surface as single and two doses in different amounts. Wound contraction and tensile strength measurements were used to evaluate the effect of Portulaca oleracea on wound healing. The results obtained indicated that Portulaca oleracea accelerates the wound healing process by decreasing the surface area of the wound and increasing the tensile strength. The greatest contraction was obtained at a single dose of 50 mg and the second greatest by two doses of 25 mg. Measurements of tensile strength and healed area were in agreement. (C) 2003 Elsevier Ireland Ltd. All rights reserved.