Criteria for predicting the outcome of pheochromocytoma by the immunohistochemical and electron microscopic findings

Morphological examination of 22 functionally active adrenal pheochromocytomas was carried out. The content of catecholamine granules in tumor cells and in the number of sustentacular cells tended to decrease in metastasizing tumors. Electron microscopy showed two types of sustentacular cells and the possibility of their apoptotic death.