期刊
JOURNAL OF BIOCHEMISTRY
卷 134, 期 4, 页码 485-489出版社
JAPANESE BIOCHEMICAL SOC
DOI: 10.1093/jb/mvg181
关键词
Arf6; cadherin; cell migration; integrin; membrane recycling and remodeling
Cell movements are essential to life, in a variety of aspects including development, repair and defence processes. Cell migration is a multifactorial process in which a number of distinct events occur simultaneously. Besides its strong appeal towards the basic sciences, the molecular mechanisms of cell migration have long been major targets of oncology, including clinical studies aiming for cancer therapy and prevention. For the further advancement of these studies, as well as for the benefit of its clinical applications, it is important to understand the fundamental machinery and mechanisms regulating cell adhesion and motility. Here the possible roles of a small GTP-binding protein, Arf6, in epithelial cell adhesion and migration, and also in cancer cell invasion, are discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据