期刊
CLINICAL BIOMECHANICS
卷 18, 期 8, 页码 765-772出版社
ELSEVIER SCI LTD
DOI: 10.1016/S0268-0033(03)00055-X
关键词
patellar tendon; mechanical properties; ligament reconstruction; tissue regeneration; blood flow
Objective. To know the temporal changes of the mechanical properties of the regenerated and the residual tissues in the patellar tendon after removal of the central portion. Design. The regenerated and the residual tissues were compared to sham-operated tendons. Background. Although the structural properties of the whole patellar tendon after removal of the central portion have been investigated. no studies have distinguished between the regenerated and the residual tissues. Methods. For 52 skeletally mature rabbits, a full-thick, segmental defect was made at the central portion of the right patellar tendon, while a sham operation performed in the left tendon. At 3, 6, 12, and 24 weeks, we evaluated the mechanical properties and fibroblast density of the regenerated and the residual tissues as well as the blood flow and tissue dimensions of the patellar tendon. In addition, non-treated patellar tendons from six rabbits were served as the control for mechanical testing. Results. The tangent modulus and the tensile strength of the regenerated tissue progressively increased with time. On the other hand, these parameters of the residual tendinous portion decreased until 6 weeks, although they gradually increased thereafter. The tensile strength of the regenerated and the residual tissues at 24 weeks were approximately 80% and 75%, respectively, of the non-treated. control tendon. Abundant blood flow and cell proliferation were observed in the regenerative tissue until 6 weeks. Conclusion. The mechanical properties of the regenerated and the residual tissues after removal of the central portion in the patellar tendon are much different from those of the original tendon.
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