Surface-enhanced Raman scattering of small molecules from silver-coated silicon nanopores

New ways of detecting low concentrations of analytes, which could be used as part of integrated on-chip devices, are offered by surface-enhanced Raman-scattering substrates fabricated on the nanoscale. The ability of metal surfaces to amplify a Raman-scattering signal (see Figure) is combined with an enlarged substrate surface area, allowing orders of magnitude enhancement for the detection of rhodamine 6G and adenine.