Organic chemistry of vitamin D analogues (deltanoids)

An increasing number of synthetic vitamin D analogues (deltanoids) are now being used as sensitive molecular biology probes and also as new drug candidates and new drugs for treatment of various human diseases. The design and stereocontrolled synthesis of such new deltanoids are guided by considering catabolism inhibition and by using large steroidal chirons and small steroid-derived chirons. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).