Bacillamide, a novel algicide from the marine bacterium, Bacillus sp SY-1, against the harmful dinoflagellate, Cochlodinium polykrikoides

Bacillamide (1) was isolated as a new algicide against the harmful dinoflagellate, Cochlodinium polykrikoides, from the marine bacterium, Bacillus sp. SY-1, and its structure was elucidated by extensive two-dimensional NMR techniques including H-1-N-15 HMBC analysis and mass analysis. Bacillamide showed algicidal activity against C. polykrikoides with LC50 of 3.2 mug/ml. (C) 2003 Elsevier Ltd. All rights reserved.