期刊
DEVELOPMENTAL CELL
卷 5, 期 5, 页码 673-690出版社
CELL PRESS
DOI: 10.1016/S1534-5807(03)00335-6
关键词
-
资金
- NHLBI NIH HHS [R01 HL67395, T32HL69766] Funding Source: Medline
Blood development in Drosophila melanogaster shares several interesting features with hematopoiesis in vertebrates, including spatiotemporal regulation as well as the use of similar transcriptional regulators and signaling pathways. In this review, we describe what is known about hematopoietic development in Drosophila and the various cell types generated and their functions. Additionally, the molecular genetic mechanisms of hernatopoietic cell fate determination and commitment within Drosophila blood cell lineages are discussed and compared to vertebrate mechanisms.
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