4.5 Article

Multicomponent exercise program improves blood lipid profile and antioxidant capacity in older women

期刊

出版社

ELSEVIER IRELAND LTD
DOI: 10.1016/j.archger.2009.05.020

关键词

Oxidative stress in aging; Antioxidant status; Lipoproteins; Physical activity in aging; Plasma lipid contents in elderly

资金

  1. Portuguese Foundation of Science and Technology [FCT/POCI/V.5/C0014/2005, SFRH/BD/36319/2007, SFRH/BPD/42525/2007]
  2. Fundação para a Ciência e a Tecnologia [SFRH/BD/36319/2007, SFRH/BPD/42525/2007] Funding Source: FCT

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This study intended to determine the effect of multicomponent exercise on blood lipid profile and on antioxidant capacity in older women. Forty women aged 60-80 years participated in a supervised multicomponent exercise program. Plasma contents of total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), apolipoprotein A-1 (Apo A-1) and apolipoprotein B (Apo B-100), total antioxidant status (TAS) and the enzymatic activities of glutathione reductase (GR) and glutathione peroxidase (GPx) were evaluated before and after 8-month training. The multicomponent exercise program induced a significant decrease in TG, TC/HDL-C and Apo B/Apo A-1 and a significant increase in HDL-C and Apo A-1 (p < 0.05). There was a significant increase in plasma TAS as well as GR and GPx enzyme activities. The present data show that an 8-month supervised moderate-intensity multicomponent exercise program resulted in beneficial improvements of blood lipid profile that were accompanied by positive modulation of antioxidant capacity. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

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