期刊
ARCHIVES OF GERONTOLOGY AND GERIATRICS
卷 50, 期 2, 页码 121-126出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.archger.2009.02.011
关键词
25-Hydroxyvitamin D-3; Physical fitness; Frail elderly women; Exercise
资金
- Japan Ministry of Education, Culture, Sports Sciences and Technology [19590621]
- Grants-in-Aid for Scientific Research [19590621] Funding Source: KAKEN
The aim of this study was to evaluate the effects of a combination of serum 25-hydroxyvitamin D-3 (25(OH)D-3) levels and exercise on physical fitness in community-dwelling frail elderly in Japan. A longitudinal survey was conducted in a town (latitude 368 north). Eighty women aged 65 years and over attended a 3-month exercise class. A face-to-face interview was conducted based on a questionnaire. The serum levels of 25(OH)D-3, intact parathyroid hormone (iPTH), were measured. Nine physical fitness tests were performed at baseline and at the end of a 3-month follow-up period. Among 80 subjects, 56.3% experienced falls, and 71.3% experienced stumbling more than once during the past year. The prevalence of 25(OH)D-3 < 50 nmol/l or 25(OH)D-3 < 75 nmol/l was 27.5% and 88.8%, respectively. Significantly greater improvements in alternate step, functional reach (FR), timed up & go (TUG), and 5-m walk, and superior functional capacity for the subjects with 25(OH)D-3 levels greater than 67.5 nmol/l (highest quartile) was observed at the end of the class. In contrast, the subjects with 25(OH)D-3 levels < 47.5 nmol/l (lowest quartile) did not improve their physical fitness. A serum 25(OH)D-3 level of greater than 47.5 nmol/l may therefore be necessary to maintain walking ability and balance. Greater than 67.5 nmol/l appears to be preferable for lower extremity strength in Japanese frail elderly women. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
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