期刊
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
卷 60, 期 12, 页码 969-976出版社
B M J PUBLISHING GROUP
DOI: 10.1136/oem.60.12.969
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资金
- NIEHS NIH HHS [T32ES07018, P30ES10126, P42ES05948] Funding Source: Medline
Aims: To estimate exposures to benzene and naphthalene among military personnel working with jet fuel (JP-8) and to determine whether naphthalene might serve as a surrogate for JP-8 in studies of health effects. Methods: Benzene and naphthalene were measured in air and breath of 326 personnel in the US Air Force, who had been assigned a priori into low, moderate, and high exposure categories for JP-8. Results: Median air concentrations for persons in the low, moderate, and high exposure categories were 3.1, 7.4, and 252 mug benzene/m(3) air, 4.6, 9.0, and 11.4 mg benzene/m(3) breath, 1.9, 10.3, and 485 mug naphthalene/m(3) air, and 0.73, 0.93, and 1.83 mug naphthalene/m(3) breath, respectively. In the moderate and high exposure categories, 5% and 15% of the benzene air concentrations, respectively, were above the 2002 threshold limit value (TLV) of 1.6 mg/m(3). Multiple regression analyses of air and breath levels revealed prominent background sources of benzene exposure, including cigarette smoke. However, naphthalene exposure was not unduly influenced by sources other than JP-8. Among heavily exposed workers, dermal contact with JP-8 contributed to air and breath concentrations along with several physical and environmental factors. Conclusions: Personnel having regular contact with JP-8 are occasionally exposed to benzene at levels above the current TLV. Among heavily exposed workers, uptake of JP-8 components occurs via both inhalation and dermal contact. Naphthalene in air and breath can serve as useful measures of exposure to JP-8 and uptake of fuel components in the body.
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