期刊
ORGANIC LETTERS
卷 5, 期 26, 页码 5035-5038出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol036071v
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资金
- NIGMS NIH HHS [GM 42897] Funding Source: Medline
[GRAPHICS] A convergent, second generation formal synthesis of (+)-Leucascandrolide A (1) has been efficiently achieved by providing a flexible, enantiocontrolled strategy toward the bioactive macrolactone component. Advancements for stereocontrol in asymmetric allylation methodology are discussed. Efforts feature novel results for reductions using the Terashima hydride reagent.
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