The effect of mannose binding lectin gene polymorphisms on susceptibility to tuberculosis in different ethnic groups

In order to investigate the role of MBL gene polymorphisms in susceptibility to tuberculosis ( TB) we genotyped 487 TB cases and 232 controls. Among African-American individuals, the frequency of B allele was lower among controls than cases (p<0.01), but we found no differences between cases and controls of white and Hispanic ethnicity.