期刊
JOURNAL OF HEALTH SCIENCE
卷 50, 期 1, 页码 97-100出版社
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/jhs.50.97
关键词
Americamysis bahia; Daphnia magna; endocrine disrupter; acute toxicity
类别
The acute toxicity of endocrine disrupters in two crustaceans, Americamysis bahia (A. bahia) and Daphnia magna (D. magna), was investigated and the toxicological responses compared. Bisphenol A had the lowest toxicity to D. magna, the 48 hr median lethal concentrations (LC50) values was 12.8 mg/l. However, the toxic sensitivity of A. bahia to bisphenol A was approximately 10-fold higher than for D. magna (48 hr LC50 ;1.34 mg/l). The 48 hr LC50 of estradiol-17beta was 2.97 and 1.69 mg/l in D. magna and A. bahia, respectively. Nonylphenol had the highest lethal toxicity against both A. bahia (48 hr LC50; 0.051 mg/l) and D. magna (48 hr LC50; 0.18 mg/l). However, ecdysteroids, and ecdysteroidal activity insecticides, such as tebufenozide, and juvenile hormone analog, had no toxic effects against either A. bahia or D. magna at the concentrations tested in this study. These results suggest that A. bahia is a more suitable toxicity test organism for endocrine disrupters than D. magna because of the higher sensitivity of A. bahia to the toxicological effect.
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