期刊
MYCOSES
卷 47, 期 1-2, 页码 4-13出版社
WILEY
DOI: 10.1046/j.1439-0507.2003.00956.x
关键词
Cladophialophora; Exophiala; Ramichloridium; Chaetothyriales; Pleosporales; Dematiaceae; melanized fungi; phaeohyphomycosis; central nervous system infections
Several types of infections of the central nervous system by melanized fungi can be distinguished: (a) single-organ infection of the cerebrum, (b) extension into the cerebrum from adjacent cavities, (c) fungal presence in the cerebrospinal fluid, or (d) meningitis. The fungal order Chaetothyriales (containing Exophiala-like black yeasts and relatives) is particularly rich in fungi causing cerebral infections. Cases by the main agents, Cladophialophora bantiana, Exophiala dermatitidis, and Ramichloridium mackenziei, published during the last 5 years are reviewed. Most of these infections prove to be fatal. Resection of the lesions in combination with antimycotic therapy may reduce mortality.
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