期刊
NATURE REVIEWS MICROBIOLOGY
卷 2, 期 2, 页码 166-173出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro822
关键词
-
类别
资金
- NIGMS NIH HHS [R01 GM091875] Funding Source: Medline
Following a sixty-year hiatus in western medicine, bacteriophages (phages) are again being advocated for treating and preventing bacterial infections. Are attempts to use phages for clinical and environmental applications more likely to succeed now than in the past? Will phage therapy and prophylaxis suffer the same fates as antibiotics - treatment failure due to acquired resistance and ever-increasing frequencies of resistant pathogens? Here, the population and evolutionary dynamics of bacterial-phage interactions that are relevant to phage therapy and prophylaxis are reviewed and illustrated with computer simulations.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据