期刊
BIOTECHNIC & HISTOCHEMISTRY
卷 79, 期 1, 页码 17-23出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10520290410001700774
关键词
chromatin; computational biology; germ cell; image cytometry; spermatozoa
资金
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [99/12765-2] Funding Source: FAPESP
We describe here a computational morphology-based approach to the investigation of possible causes of chromatin alterations in sperm. A comprehensive set of state-of-the-art and geometric measures are computationally extracted from toluidine blue stained images and analyzed to infer the possible processes leading to normal and abnormal chromatin formation while seeking a possible taxonomy of chromatin alterations and their influence on sperm head morphology. Using this methodology, we have identified higher chromatin fragility at some specific points of the sperm head. Despite the lack of correlation between morphologies of sperm head and chromatin structure, four main morphological types of chromatin alterations in bull spermatozoa have been identified and their possible causes discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据