4.7 Article

Statin use and cancer risk in the General Practice Research Database

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BRITISH JOURNAL OF CANCER
卷 90, 期 3, 页码 635-637

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NATURE PUBLISHING GROUP
DOI: 10.1038/sj.bjc.6601566

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3-hydroxy-3-methylglutaryl coenzyme A inhibitors; statins; hyperlipidaemia; epidemiology

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In a matched case-control study using the General Practice Research Database, current statin use was not associated with a significantly altered risk of any of 13 studied cancers. Untreated hyperlipidaemia was associated with slightly increased risks of colon cancer (relative risk 1.8; 95% confidence interval 1.2-2.8), prostate cancer (1.5; 1.1-2.0), and bladder cancer (1.9; 1.2-3.1).

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