期刊
NEUROSCIENCE LETTERS
卷 356, 期 2, 页码 115-118出版社
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/j.neulet.2003.11.032
关键词
circadian rhythm; dark; light; melatonin; night; sleep
资金
- NHLBI NIH HHS [R01 HL072408] Funding Source: Medline
- NINDS NIH HHS [R01 NS035695] Funding Source: Medline
Short sleep/dark durations are common in modem society. In a within subjects counterbalanced design, we compared the effect of 7-19 nights with a late bedtime (01:00) versus 7-19 nights with an early bedtime (22:00) on the human dim light melatonin rhythm. All ten healthy subjects experienced lights on time at 07:00 and at least 5 min of outdoor light between 07:00 and 08:00. We found that despite the morning light exposure, the melatonin rhythm following the late bedtime nights was delayed by similar to0.6 h (P < 0.05), as compared to after the early bedtime nights. These results suggest that when people truncate their sleep by delaying their bedtime they also significantly phase delay their circadian rhythms and/or when people advance their bedtime their circadian rhythms advance. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
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