Radio-frequency driven polarization transfer without heteronuclear decoupling in rotating solids

This Letter reports significant excitation of C-13 homonuclear double-quantum coherence in a solid-state magic-angle-spinning NMR experiment, acquired without heteronuclear decoupling of abundant H-1 spins. The heteronuclear decoupling efficiency of a group of existing homonuclear polarization transfer sequences are investigated and optimal schemes are identified. Since the approach permits the application of fast MAS and significantly reduces the total radio-frequency power used, it is particularly well suited to biomolecular applications at ultra-high magnetic fields. (C) 2004 Elsevier B.V. All rights reserved.