期刊
ARCHIVES OF DERMATOLOGY
卷 148, 期 10, 页码 1159-1164出版社
AMER MEDICAL ASSOC
DOI: 10.1001/archdermatol.2012.1060
关键词
-
类别
资金
- Carlos III Health Institute Research Fund for Research in Health Technology [PI 07/00735]
- Mutua Madrilena Foundation for Medical Research [BE67392009]
Objective: To validate dermoscopy as a real-time noninvasive diagnostic imaging technique for actinic keratosis (AK). Design: Prospective study to validate a diagnostic test. Setting: Dermatology department of a tertiary university hospital in Fuenlabrada, Madrid, Spain. Patients: A total of 178 patients with a clinical diagnosis of AK participated in the study. Main Outcome Measures: An independent blinded comparison was performed between dermoscopy results and histopathological findings, the gold standard for the diagnosis of AK. All the patients underwent both diagnostic tests. Results: One hundred seventy-eight lesions were evaluated. The concordance between dermoscopy results and histopathological findings was 0.917. The sensitivity of dermoscopy for the diagnosis of AK was 98.7%, with a specificity of 95.0%, a positive likelihood ratio of 19.74, and a negative likelihood ratio of 0.01. A diagnostic algorithm that combined follicular openings and erythematous pseudonetwork demonstrated a sensitivity of 95.6% and a specificity of 95.0% for the diagnosis of AK. Conclusions: The sensitivity and specificity of dermoscopy for the diagnosis of AK were high, as was the concordance between dermoscopy results and histopathological findings. As a real-time noninvasive diagnostic imaging technique for AK, dermoscopy may be incorporated in the management of patients with these lesions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据