Diethoxyphosphinyl acetic acid hydrazide:: a uniquely versatile reagent for the preparation of fused [5,5]-, [5,6]-, and [5,7]-3-[(E)-2(arylvinyl)]-1,2,4-triazoles

Diethoxyphosphinyl acetic acid hydrazide is a unique reagent that provides a convenient and efficient process to prepare fused [5,5]-, [5,6]-, and [5,7]-3-[(E)-2-(arylvinyl)]-1,2,4-triazoles from aldehydes and alkoxyimines. The process involves three steps without isolation of any intermediates to afford 1,2,4-triazoles in modest to excellent overall yield. (C) 2004 Elsevier Ltd. All rights reserved.