期刊
PLANT BIOTECHNOLOGY JOURNAL
卷 2, 期 2, 页码 83-100出版社
BLACKWELL PUBLISHING LTD
DOI: 10.1111/j.1467-7652.2004.00062.x
关键词
antibody; biotechnology; glycosylation; molecular farming; plant-made pharmaceuticals; recombinant protein; transgenic plant
Antibodies have long been recognized for their diagnostic and therapeutic potential. The rapidly increasing number of monoclonal antibodies approved for immunotherapy has paved the way to an even greater demand for these molecules. In order to satisfy this growing demand and to increase the production capacity, alternative systems based on antibody production in transgenic organisms are being actively explored. In this paper, we focus on transgenic plants as a promising system for the scale-up and processing of plant-made pharmaceuticals. In particular, we point out the advantages and limitations induced by glycosylation of plant-made antibodies for human therapy.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据