期刊
INTERNATIONAL JOURNAL OF TOXICOLOGY
卷 23, 期 2, 页码 91-95出版社
SAGE PUBLICATIONS INC
DOI: 10.1080/10915810490435604
关键词
chlordane; endocrine disruption chemicals; lindane; Neocaridina denticulata; testosterone; vitellogenin
The purpose of this study was to investigate the acute toxicity of chlordane and lindane as well as their endocrine disruption effect on green neon shrimp (Neocaridina denticulata), a common habitant in freshwater system of eastern Asia and Hawaii. First, the organisms were exposed to chlordane and lindane to estimate the 96-h LC50 (96-h median lethal concentration). Then, levels of testosterone and vitellogenin in hemolymph of N. denticulata after exposure to sublethal concentrations of chlordane (1 ng/L and 10 ng/L) and lindane (0.1 mug/L and 1 mug/L) were also examined. The 96-h LC50 values obtained from the results of acute exposure were 127.03 (130.11-122.35) ng/L and 9.36 (8.00-10.96) mug/L for chlordane and lindane, respectively. Furthermore, reductions of testosterone concentration were observed in both chlordane- and lindane-treated shrimps, whereas induction of vitellogenin-like protein was only apparent in chlordane-treated shrimps. Thus, it is concluded that chlordane and lindane may probably show some disruption endocrine functions on N. denticulata .
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