期刊
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY
卷 28, 期 3, 页码 254-261出版社
OXFORD UNIV PRESS
DOI: 10.1093/arclin/act018
关键词
Schizophrenia; Semantic processing; Olfactory; Olfaction; Smell; Boston naming test
资金
- National Institutes of Health [MH-63381, MH-59852]
- Independent Investigator Award from the Brain Behavior Research Fund
- Hofmann Trust
Despite the well-documented observation of odor identification deficits in schizophrenia, less is known about where the disruption in the process of correctly identifying an odor occurs. This study aimed to determine the potential moderating effects of semantic processing on the observed olfactory dysfunction in schizophrenia. Schizophrenia patients and healthy comparison subjects completed two versions of the University of Pennsylvania Smell Identification Test (UPSIT): an uncued free-response version and the standard multiple-choice paradigm, as well as three semantic measures: The Boston Naming Test, Animal Naming, and Pyramids and Palm Tree Test. Schizophrenia patients yielded significantly lower scores than the comparison group on the standard UPSIT and on semantic measures. No relationship was observed between olfactory and semantic task performance in patients. These data suggest that odor identification deficits may not be primarily due to semantic processing deficits in schizophrenia.
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