期刊
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY
卷 24, 期 6, 页码 547-554出版社
OXFORD UNIV PRESS
DOI: 10.1093/arclin/acp046
关键词
HIV; Neuropsychological function; Adherence; Medication compliance; Substance use
资金
- MIR [R01 DA15215]
- VISN 1 MIRECC [P50 DA09241]
Prospective memory is defined as the ability to remember to remember something at a future time despite intervening distractions and may be particularly important in remembering to take prescribed medication among people infected with HIV. Ninety-seven HIV-positive participants in a clinical trial had their adherence measured by electronic pillcaps and were administered neuropsychological screening tests and the memory for intentions screening test (MIST). Factor analysis of the MIST and other neuropsychological measures identified four factors. Two were derived from MIST subscales and accounted for approximately 50% of the variance in cognitive functioning. Only one factor was significantly correlated with adherence, and this was a MIST factor. In this preliminary study, the MIST assessed a memory function that (a) could be distinguished from traditional retrospective recall and executive functioning and (b) was correlated with antiretroviral adherence.
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