期刊
MAGNETIC RESONANCE IN MEDICINE
卷 51, 期 3, 页码 568-576出版社
WILEY
DOI: 10.1002/mrm.10729
关键词
moving-table MRI; peripheral MRA; time-resolved 3D MRA; extended-FOV MRI; contrast kinetics
资金
- NHLBI NIH HHS [HL70620, HL37310] Funding Source: Medline
- NIBIB NIH HHS [EB00212] Funding Source: Medline
A method is presented for acquiring 3D time-resolved MR images of an extended (> 100 cm) longitudinal field of view (FOV), as used for peripheral MR angiographic runoff studies. Previous techniques for long-FOV peripheral MRA have generally provided a single image (i.e., with no time resolution). The technique presented here generates a time series of 3D images of the FOV that lies within the homogeneous volume of the magnet. This is achieved by differential sampling of 3D k-space during continuous motion of the patient table. Each point in the object is interrogated in five consecutive 3D image sets generated at 2.5-s intervals. The method was tested experimentally in eight human subjects, and the leading edge of the bolus was observed in real time and maintained within the imaging FOV. The data revealed differential bolus velocities along the vasculature of the legs. (C) 2004 Wiley-Liss, Inc.
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