期刊
JOURNAL OF AFFECTIVE DISORDERS
卷 78, 期 3, 页码 253-257出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/S0165-0327(02)00308-7
关键词
mania; treatment; transcranial magnetic stimulation (TMS); prefrontal cortex; laterality
Background: Transcranial magnetic stimulation (TMS) has been suggested for the treatment of a variety of CNS disorders including depression and mania. Methods: Nine bipolar (1) in-patients diagnosed with mania were treated with right prefrontal rapid TMS in an open and prospective study. Eight of nine patients received TMS as add-on treatment to an insufficient or only partially effective drug therapy. Results: During the 4 weeks of TMS treatment a sustained reduction of manic symptoms as measured by the Bech-Rafaelsen mania scale (BRMAS) was observed in all patients. Limitations: Due to the open and add-on design of the study, a clear causal relationship between TMS treatment and reduction of manic symptoms cannot be established. Conclusions: Our data suggest that right prefrontal, rapid TMS is safe and efficacious in the add-on treatment of bipolar mania showing laterality opposed to the proposed effect of rapid TMS in depression. (C) 2004 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据