期刊
TETRAHEDRON LETTERS
卷 45, 期 10, 页码 2203-2205出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.01.027
关键词
Latia neritoides; luciferin; luciferase; bioluminescence; enol ester
The bioluminescent system of the univalve shell Latia neritoides exhibits a luciferin-luciferase reaction. We study the enol formate structure of Latia luciferin, which is expected to be important for luminescent activity. The Latia luciferin analogues with an enol substituted benzoate moiety were synthesized and their bioluminescent activity was measured. The Latia luciferin benzoate analogues delay emission for natural luciferin in bioluminescence, indicating that the Latia bioluminesent activity can be controlled by the design of the enol ester. (C) 2004 Elsevier Ltd. All rights reserved.
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