期刊
GROWTH FACTORS
卷 22, 期 1, 页码 13-18出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/08977190410001688687
关键词
transforming growth factor-beta; inhibin; activin; betaglycan
资金
- NICHD NIH HHS [HD041857, HD037096] Funding Source: Medline
Inhibin is best known as a reproductive hormone that inhibits release of follicle-stimulating hormone (FSH) from the pituitary gland. Over the last decade or so a number of other biological roles have emerged, putting inhibin more in the class of a growth factor. Despite this, little is known of the signalling pathways for this protein. This minireview summarises the pertinent aspects of inhibin biology and focuses on four potential signalling mechanisms through which inhibin might influence cellular function, namely subunit availability, receptor assembly, co-receptors and signalling through inhibin-specific signalling pathways.
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